MIB1/DIP1 Rabbit mAb (AMR11902N)

• Background:

  This gene encodes a protein containing multiple ankyrin repeats and RING finger domains that functions as an E3 ubiquitin ligase. The encoded protein positively regulates Notch signaling by ubiquitinating the Notch receptors, thereby facilitating their endocytosis. This protein may also promote the ubiquitination and degradation of death-associated protein kinase 1 (DAPK1) . [provided by RefSeq, Jun 2013]

• Synonyms:

  DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6

• Gene ID:

  57534

• UniProt:

  Q86YT6

• Cellular Locus:

  Cell membrane, Cytoplasm, centriolar satellite, centrosome, cytoskeleton, microtubule organizing center

• Dilution:

  WB 1:500 - 1:2000

• Form:

  Liquid

• Buffer:

  Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.

• Molecular Weight:

  Calculated MW: 110kDa Observed MW: 110kDa

• Storage Conditions:

  Store at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MIB1/DIP1 Rabbit mAb (AMR11902N) .

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57534

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q86YT6

• AA Sequence:

  Email for sequence