Integrin beta 1 (ITGB1) Mouse Monoclonal Antibody [Clone ID: LBI9B5]

• Background:

  Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Synonyms:

  CD29; FNRB; GPIIA; MDF2; MSK12; VLA-BETA; VLAB

• Gene Name:

  Homo sapiens integrin subunit beta 1 (ITGB1), transcript variant 1A, mRNA.

• Gene ID:

  3688

• UniProt:

  P05556

• Conjugation:

  Unconjugated

• Related Pathways:

  Arrhythmogenic right ventricular cardiomyopathy (ARVC), Axon guidance, Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer

• Field of Research:

  Arrhythmogenic right ventricular cardiomyopathy (ARVC), Axon guidance, Cell adhesion molecules (CAMs), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hypertrophic cardiomyopathy (HCM), Leukocyte transendothelial migration, Pathogenic Escherichia coli infection, Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer

• Dilution:

  WB 1:500, IHC 1:150

• Form:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Buffer:

  Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

• Storage Conditions:

  Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  ITGB1

• Overview:

  Carrier-free (BSA/glycerol-free) ITGB1 mouse monoclonal antibody, clone LBI9B5

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=3688

• Uniprot URL:

  https://www.uniprot.org/uniprot/P05556