BCL2 Mouse Monoclonal Antibody [Clone ID: UMLBI225]

• Background:

  This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Two transcript variants, produced by alternate splicing, differ in their C-terminal ends. [provided by RefSeq, Jul 2008]

• Synonyms:

  Bcl-2; PPP1R50

• Gene Name:

  Homo sapiens BCL2 apoptosis regulator (BCL2), transcript variant alpha, mRNA.

• Gene ID:

  596

• UniProt:

  P10415

• Conjugation:

  Unconjugated

• Related Pathways:

  Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer

• Field of Research:

  Amyotrophic lateral sclerosis (ALS), Apoptosis, Colorectal cancer, Focal adhesion, Neurotrophin signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer

• Concentration:

  0.5~1.0 mg/ml (Lot Dependent)

• Dilution:

  IHC 1:500

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transmembrane

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  BCL2

• Overview:

  BCL2 mouse monoclonal antibody, clone UMLBI225

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=596

• Uniprot URL:

  https://www.uniprot.org/uniprot/P10415