TGF beta 1 (TGFB1) Mouse Monoclonal Antibody [Clone ID: LBI1E12]

• Background:

  This gene encodes a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Oct

• Synonyms:

  CED; DPD1; LAP; TGFB; TGFbeta

• Gene Name:

  Transforming growth factor beta 1

• Gene ID:

  7040

• UniProt:

  P01137

• Conjugation:

  Unconjugated

• Related Pathways:

  Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, TGF-beta signaling pathway

• Field of Research:

  Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Cytokine-cytokine receptor interaction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway, Pancreatic cancer, Pathways in cancer, Renal cell carcinoma, TGF-beta signaling pathway

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:1000, IF 1:100, FLOW 1:50

• Form:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, ES Cell Differentiation/IPS, Secreted Protein, Transcription Factors

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  TGFB1

• Overview:

  TGFB1 mouse monoclonal antibody, clone LBI1E12

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=7040

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01137