CYB5R3 Mouse Monoclonal Antibody [Clone ID: LBI1E3]

• Background:

  This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias. [provided by RefSeq]

• Synonyms:

  B5R; DIA1

• Gene Name:

  Cytochrome b5 reductase 3

• Gene ID:

  1727

• UniProt:

  P00387

• Conjugation:

  Unconjugated

• Related Pathways:

  Amino sugar and nucleotide sugar metabolism

• Field of Research:

  Amino sugar and nucleotide sugar metabolism

• Concentration:

  0.7 mg/ml

• Dilution:

  WB 1:500, IF 1:100

• Form:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  CYB5R3

• Overview:

  Anti-CYB5R3 mouse monoclonal antibody, clone LBI1E3

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1727

• Uniprot URL:

  https://www.uniprot.org/uniprot/P00387