TRIM22 Antibody - N-terminal region: HRP (P100888_P050-HRP)

• Gene Name:

  Tripartite motif containing 22

• Gene Aliases:

  RNF94, STAF50, GPSTAF50

• Gene ID:

  10346

• Swiss Prot:

  Q8IYM9

• Accession Number:

  NP_006065

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human TRIM22

• Target:

  TRIM22 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. It localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects.The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• Partner Proteins:

  EIF4E; UBC; TAB2; CASK; CIC; TRIM22; USP7; RERE; ZZZ3; TAF7; CREB1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  57kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  498

• NCBI Gene Symbol:

  TRIM22

• Protein Name:

  E3 ubiquitin-protein ligase TRIM22

• Nucleotide Accession Number:

  NM_006074