GPS2 Antibody - C-terminal region: FITC (ARP72703_P050-FITC)

• Gene Aliases:

  AMF-1

• Gene ID:

  2874

• Swiss Prot:

  Q13227

• Accession Number:

  XP_005256674

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPS2

• Target:

  This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function.

• Partner Proteins:

  ATF4; TFIP11; RBPMS; RALBP1; KRT31; SESTD1; NCOR2; HDAC3; SUMO1; UBC; TBL1X; TBL1XR1; vif; MSH5; MSH4; Nr0b2; NR1H4; HNF4A; HDAC1; NR5A2; HDAC5; THRB; THRA; CNOT2; SIN3A; PBK; C19orf57; GPS2; MAP3K7CL; CHD3; SPDL1; SETDB1; CCNA1; EP300; GOLGA2; NCOR1; TP5

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  35kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  327

• NCBI Gene Symbol:

  GPS2