PKP4 Antibody - N-terminal region: HRP (ARP64810_P050-HRP)

• Gene Name:

  Plakophilin 4

• Gene Aliases:

  P0071

• Gene ID:

  8502

• Swiss Prot:

  Q99569-2

• Accession Number:

  NP_001005476

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

• Target:

  Armadillo-like proteins are characterized by a series of armadillo repeats, first defined in the Drosophila 'armadillo' gene product, that are typically 42 to 45 amino acids in length. These proteins can be divided into subfamilies based on their number of repeats, their overall sequence similarity, and the dispersion of the repeats throughout their sequences. Members of the p120 (ctn) /plakophilin subfamily of Armadillo-like proteins, including CTNND1, CTNND2, PKP1, PKP2, PKP4, and ARVCF. PKP4 may be a component of desmosomal plaque and other adhesion plaques and is thought to be involved in regulating junctional plaque organization and cadherin function. Multiple transcript variants have been found for this gene, but the full-length nature of only two of them have been described so far.

• Partner Proteins:

  ATPAF2; LZTS2; UBC; GOLGA2; TRIM23; SAV1; LATS2; LATS1; PAXIP1; ATP6V1B1; LNX1; OSGEP; MINK1; PDZD2; ERBB2IP; GABARAP; CDH5; DSC3; PGAM1; DSP; PSEN1; CDH2; CDH1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  PKP4 is strongly supported by BioGPS gene expression data to be expressed in HeLa

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 93%; Rat: 86%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  127kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  1149

• NCBI Gene Symbol:

  PKP4

• Protein Name:

  Plakophilin-4

• Nucleotide Accession Number:

  NM_001005476