PSTPIP1 Antibody - N-terminal region: Biotin (ARP64283_P050-Biotin)

• Gene Name:

  Proline-serine-threonine phosphatase interacting protein 1

• Gene Aliases:

  H-PIP, PAPAS, CD2BP1, PSTPIP, CD2BP1L, CD2BP1S

• Gene ID:

  9051

• Swiss Prot:

  O43586

• Accession Number:

  NP_003969

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

• Target:

  The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.

• Partner Proteins:

  RTP5; TRAF3IP3; FBXL18; SH2D4A; PCDHB14; UBE2W; FAM90A1; PRPF31; LSM4; BUB3; ZNF175; TULP3; SPG7; SDCBP; MVP; WASL; DNM2; MED28; SHBG; KHDRBS1; WAS; TUBB; WIPF1; HSPA1A; CARS; ACTB; PTPN18; WASF2; WASF1; CD2AP; PTPN12; MEFV; ABL1; CD2; FASLG; BZW2; RPL36

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 79%; Rat: 100%; Zebrafish: 92%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  47kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  416

• NCBI Gene Symbol:

  PSTPIP1

• Protein Name:

  Proline-serine-threonine phosphatase-interacting protein 1

• Nucleotide Accession Number:

  NM_003978