TNFRSF4 Antibody - middle region: Biotin (ARP59086_P050-Biotin)

• Gene Name:

  Tumor necrosis factor receptor superfamily, member 4

• Gene Aliases:

  OX40, ACT35, CD134, IMD16, TXGP1L

• Gene ID:

  7293

• Swiss Prot:

  P43489

• Accession Number:

  NP_003318

• Host:

  Rabbit

• Reactivity:

  Human, Pig

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human TNFRSF4

• Target:

  The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation.

• Partner Proteins:

  TRAF4; TRAF5; TRAF3; TRAF2; TRAF1; TNFRSF9; SIVA1; TNFSF4

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  TNFRSF4 is strongly supported by BioGPS gene expression data to be expressed in 721_B

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%; Pig: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  27kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  277

• NCBI Gene Symbol:

  TNFRSF4

• Protein Name:

  Tumor necrosis factor receptor superfamily member 4

• Nucleotide Accession Number:

  NM_003327