BUB3 Antibody - N-terminal region: Biotin (ARP58599_P050-Biotin)

• Gene Name:

  Budding uninhibited by benzimidazoles 3 homolog (yeast)

• Gene Aliases:

  BUB3L, hBUB3

• Gene ID:

  9184

• Swiss Prot:

  A6NJ42

• Accession Number:

  NP_001007794

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human BUB3

• Target:

  BUB3 is required for kinetochore localization of BUB1.This gene encodes a protein involved in spindle checkpoint function. The encoded protein contains four WD repeat domains and has sequence similarity with the yeast BUB3 protein. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Partner Proteins:

  BUB1B; BUB1; HUWE1; PSTPIP1; UBC; SUMO2; CDC20; NEDD8; SUMO1; RPA3; RPA2; RPA1; WBP4; CLIP1; EGFR; ZNF207; VCAM1; UBA1; THRA; RPL37A; ITGA4; FN1; NKAP; EXOC3; SUGT1; CPNE1; ANAPC4; SEPT2; TOP1; SMAD3; SMAD2; Mad2l1; COPS5; CUL3; SF3A2; ELAVL1; CDC27; HDGF

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF, IHC

• Purification:

  Affinity Purified

• Sample Type:

  BUB3 is strongly supported by BioGPS gene expression data to be expressed in HEK293T, PANC1

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  36kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  326

• NCBI Gene Symbol:

  BUB3

• Protein Name:

  Mitotic checkpoint protein BUB3

• Nucleotide Accession Number:

  NM_001007793