NECAB3 Antibody - N-terminal region: Biotin (ARP57669_P050-Biotin)

• Gene Name:

  N-terminal EF-hand calcium binding protein 3

• Gene Aliases:

  NIP1, XB51, STIP3, EFCBP3, SYTIP2, APBA2BP, dJ63M2.4, dJ63M2.5

• Gene ID:

  63941

• Swiss Prot:

  Q96P71

• Accession Number:

  NP_112509

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Horse, Pig, Yeast

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human NECAB3

• Target:

  The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene.

• Partner Proteins:

  UBC; APP; MYC; IKBKG; APBA2

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 79%; Dog: 90%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 90%; Rat: 90%; Yeast: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  44kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  396

• NCBI Gene Symbol:

  NECAB3

• Protein Name:

  N-terminal EF-hand calcium-binding protein 3

• Nucleotide Accession Number:

  NM_031232