PEG10 Antibody - C-terminal region: HRP (ARP51312_P050-HRP)

• Gene Name:

  Paternally expressed 10

• Gene Aliases:

  EDR, HB-1, Mar2, RTL2, MEF3L, Mart2, RGAG3, SIRH1

• Gene ID:

  23089

• Accession Number:

  NP_001165909

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C-terminal region of Human PEG10

• Target:

  This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene.

• Partner Proteins:

  SIAH1; FAM127C; LDOC1; CALCOCO2; FAM127A; UBC; MAPT; HNRNPUL1; HNRNPH1; BAG1; TGFBR2; TGFBR1; BMPR1B; BMPR1A; ACVRL1; ACVR2B; ACVR2A; ACVR1B; ACVR1; RNF2; ZNF512B; RNF181; HMGCS1; TOLLIP; IRF4; SIAH2

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rabbit: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  44kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  401

• NCBI Gene Symbol:

  PEG10

• Nucleotide Accession Number:

  NM_001172438