SURF4 Antibody - N-terminal region: HRP (ARP50161_P050-HRP)

• Gene Name:

  Surfeit 4

• Gene Aliases:

  ERV29

• Gene ID:

  6836

• Swiss Prot:

  O15260

• Accession Number:

  NP_149351

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Pig, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human SURF4

• Target:

  SURF4 is a conserved integral membrane protein containing multiple putative transmembrane regions. In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs) . The specific function of this protein has not been determined but its yeast homolog is directly required for packaging glycosylated pro-alpha-factor into COPII vesicles. This gene is located in the surfeit gene cluster, which is comprised of very tightly linked housekeeping genes that do not share sequence similarity. The encoded protein is a conserved integral membrane protein containing multiple putative transmembrane regions. In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs) . The specific function of this protein has not been determined but its yeast homolog is directly required for packaging glycosylated pro-alpha-factor into COPII vesicles. This gene uses multiple polyadenylation sites, resulting in transcript length variation. The existence of alternatively spliced transcript variants has been suggested, but their validity has not been determined.

• Partner Proteins:

  UBC; LGR4; MMS19; env; UBL4A; VKORC1; SRSF5; SRSF1; SAFB; S100A9; PSAP; P4HB; NPM1; NHP2L1; NFIA; SEPT2; HSPA5; SEPT7; NDUFB11; HP1BP3; PHGDH; SF3B1; NCSTN; SAP18; SRSF7; TMEM173; UNC93B1; C20orf24; SERINC3; DEGS1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  30kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  269

• NCBI Gene Symbol:

  SURF4

• Protein Name:

  Surfeit locus protein 4

• Nucleotide Accession Number:

  NM_033161