HACE1 Antibody - middle region: HRP (ARP43277_P050-HRP)

• Gene Name:

  HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

• Gene Aliases:

  SPPRS

• Gene ID:

  57531

• Swiss Prot:

  Q8IYU2

• Accession Number:

  NP_065822

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human HACE1

• Target:

  HACE1 contains 6 ANK repeats and 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain. HACE1 is an E3 ubiquitin-protein ligase that may function in cellular proteins degradation.

• Partner Proteins:

  UBE2L3; UBC; OPTN; Unc45b; Flna; Actn1; Cald1; Lima1; Actn4; Tpm3; Tmod3; Coro1c; Vim; Vcl; Tubb5; Tubb4a; Tpm2; Tpm1; Tcp1; Plec; Sqstm1; Npm1; Myh9; Marcks; Hspa9; Hsp90ab1; Hspd1; Hspa8; Fhl1; Csrp1; Cnn2; Cct8; Serpinh1; Capzb; Capza2; Capza1; Actg1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  102kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  909

• NCBI Gene Symbol:

  HACE1

• Protein Name:

  E3 ubiquitin-protein ligase HACE1

• Nucleotide Accession Number:

  NM_020771