NXF5 Antibody - middle region: HRP (ARP41062_T100-HRP)

• Gene Name:

  Nuclear RNA export factor 5

• Gene ID:

  55998

• Swiss Prot:

  Q9H1B4

• Accession Number:

  NP_116564

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human NXF5

• Target:

  NXF5 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2) -like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2) -like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. Five transcript variants that encode different isoforms have been found for this gene.

• Partner Proteins:

  NXF1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Concentration:

  0.5 mg/mL

• Homology:

  Dog: 86%; Human: 100%; Mouse: 79%; Rabbit: 86%; Rat: 86%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  44kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  397

• NCBI Gene Symbol:

  NXF5

• Protein Name:

  Nuclear RNA export factor 5

• Nucleotide Accession Number:

  NM_032946