NR1H2 Antibody - N-terminal region: HRP (ARP38906_T100-HRP)

• Gene Name:

  Nuclear receptor subfamily 1, group H, member 2

• Gene Aliases:

  NER, UNR, LXRB, LXR-b, NER-I, RIP15

• Gene ID:

  7376

• Swiss Prot:

  Q68CY8

• Accession Number:

  NP_009052

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Dog, Guinea Pig, Horse

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human NR1H2

• Target:

  The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA) and beta, are known to encode LXR proteins.The LX receptors (LXRs) were originally identified as orphan members of the nuclear receptor superfamily because their ligands were unknown. Like other receptors in the family, LXRs heterodimerize with retinoid X receptor (see MIM 180245) and bind to specific response elements (LXREs) characterized by direct repeats separated by 4 nucleotides. Two genes, alpha (LXRA, MIM 602423) and beta, are known to encode LXR proteins (Song et al., 1995) .[supplied by OMIM].

• Partner Proteins:

  RXRG; MDFI; KDM1A; SUV39H1; ACVRL1; LAMC3; NCOR2; YY1; NPY; CDKN1A; PPARGC1B; PDCD4; PIAS1; USP7; PRKCA; SENP3; CORO2A; MPP1; COL4A5; CHD3; RMI1; CSAD; DUSP12; C14orf1; FAF1; SPRY2; HMGXB4; SORBS2; BAG6; VIM; UBE2D1; SMPD1; ROBO2; NCOR1; NRIP1; NCOA3; VDR

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Concentration:

  0.5 mg/mL

• Homology:

  Dog: 90%; Guinea Pig: 86%; Horse: 79%; Human: 100%; Rat: 86%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  51kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  460

• Applications Notes:

  ChIP

• NCBI Gene Symbol:

  NR1H2

• Protein Name:

  Putative uncharacterized protein DKFZp686D1580 EMBL CAH18442.1

• Nucleotide Accession Number:

  NM_007121