ASGR2 Antibody - N-terminal region: FITC (ARP33820_P050-FITC)

• Gene Name:

  Asialoglycoprotein receptor 2

• Gene Aliases:

  HL-2, HBXBP, ASGPR2, ASGP-R2, CLEC4H2

• Gene ID:

  433

• Swiss Prot:

  P07307

• Accession Number:

  NP_001172

• Host:

  Rabbit

• Reactivity:

  Human, Rat, Pig, Yeast

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR2

• Target:

  This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

• Partner Proteins:

  HDAC3; UBC; CDK6; CDK4; COPS5; TADA3; CDKN2A

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%; Pig: 77%; Rat: 79%; Yeast: 77%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  35kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  311

• NCBI Gene Symbol:

  ASGR2

• Protein Name:

  Asialoglycoprotein receptor 2

• Nucleotide Accession Number:

  NM_001181