HSPA9 Antibody - C-terminal region: Biotin (ARP30175_P050-Biotin)

• Gene Name:

  Heat shock 70kDa protein 9 (mortalin)

• Gene Aliases:

  CSA, MOT, MOT2, SAAN, CRP40, EVPLS, GRP75, PBP74, GRP-75, HSPA9B, SIDBA4, MTHSP75, HEL-S-124m

• Gene ID:

  3313

• Swiss Prot:

  P38646

• Accession Number:

  NP_004125

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human HSPA9

• Target:

  HSPA9 belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA9 is a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone.CSHL1 is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. This particular family member is expressed in placental villi, although it was originally thought to be a pseudogene. In fact, alternative splicing suggests that the majority of the transcripts would be unable to express a secreted protein.The product encoded by this gene belongs to the heat shock protein 70 family which contains both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. This gene encodes a heat-shock cognate protein. This protein plays a role in the control of cell proliferation. It may also act as a chaperone. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications. The protein encoded by this gene is an inositol 1,4,5-trisphosphate (InsP3) 5-phosphatase and contains a Sac domain. The activity of this protein is specific for phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. Alternatively spliced transcript variants have been observed, but most of them are not thought to be protein-coding.

• Partner Proteins:

  GPX7; FUS; CDKN2A; UBC; TP53; YKT6; CDKN1A; CDC20; CEP250; TUBGCP2; CEP57; AURKB; TUBG1; AURKA; SUMO2; SUMO3; NEDD1; SPRTN; CEP76; HAUS2; TUBGCP4; STAU1; GRSF1; NEDD8; MDM2; EED; RAP1GDS1; PFAS; GINS3; ATG3; OSGEP; BZW2; ABHD14A; TNFAIP8; FERMT2; AIP; CNB

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  IHC, IP, WB

• Purification:

  Affinity Purified

• Sample Type:

  HSPA9 is strongly supported by BioGPS gene expression data to be expressed in HEK293T

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 85%; Dog: 92%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  75kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  679

• NCBI Gene Symbol:

  HSPA9

• Protein Name:

  Stress-70 protein, mitochondrial

• Nucleotide Accession Number:

  NM_004134