Recombinant 2019-nCoV 3C-like Proteinase (N-6His)

• Background:

  The viral main proteinase (M pro , also called 3CL pro), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents.

• Description:

  Recombinant 2019-nCoV 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser1-Gln306 is expressed with a 6His tag at the N-terminus.

• Synonyms:

  M Proteinase; 3CL Proteinase

• UniProt:

  YP_009725301.1

• Accession Number:

  YP_009725301.1

• Purity:

  Greater than 95% as determined by reducing SDS-PAGE.

• Molecular Weight:

  36.1 KDa

• Shipping Conditions:

  The product is shipped on dry ice/polar packs. Upon receipt, store it immediately at the temperature listed below.

• Storage Conditions:

  Store at ≤-70°C, stable for 6 months after receipt. Store at ≤-70°C, stable for 3 months under sterile conditions after opening. Please minimize freeze-thaw cycles.

• Notes:

  Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Observed Molecular Weight:

  33 KDa, reducing conditions

• Other Product Names:

  M Proteinase; 3CL Proteinase

• CAS Number:

  9000-83-3