PROTAC BRD4 ligand-1

• UNSPSC Description:

  PROTAC BRD4 ligand-1 is a potent BET inhibitor and a ligand for target BRD4 protein for PROTACT GNE-987 (HY-129937A)[1].

• Target Antigen:

  Epigenetic Reader Domain; Ligands for Target Protein for PROTAC

• Type:

  Reference compound

• Related Pathways:

  Epigenetics;PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/protac-brd4-ligand-1.html

• Purity:

  99.85

• Solubility:

  DMSO : 5 mg/mL (ultrasonic)

• Smiles:

  O=C(C1=C(CS(=O)(C)=O)C=C(C(N(C2=NC=C(F)C=C2F)C3)=C1)C4=CN(C)C(C5=C4C3=CN5)=O)O

• Molecular Weight:

  500.47

• References & Citations:

  [1]Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2313230-51-0