Recombinant Human CXCL6/GCP-2 Protein (Trx Tag)

• Background:

  Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2. In addition to its chemotactic and angiogenic properties , it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7.

• Abbreviation:

  CXCL6/GCP-2

• Synonyms:

  CKA; CXCL; SCYB; Chemokine Alpha; C-X-C Motif Chemokine; Small-Inducible Cytokine B; GCP; CXCL6; CKA-3; GCP-2; GCP2; SCYB6; Chemokine Alpha 3; C-X-C Motif Chemokine 6; Granulocyte Chemotactic Protein 2; Granulocyte Chemotactic Protein-2; Small-Inducible Cytokine B6; C X C motif chemokine 6; Chemokine (C X C motif) ligand 6; CKA 3; CKA3; CXCL 6; GCP 2; N-processed variant 3; Small inducible cytokine B6; Small inducible cytokine subfamily B (Cys X Cys) member 6; Small inducible cytokine subfamily B (Cys X Cys) member b

• UniProt:

  P80162

• Accession Number:

  P80162

• Expression System:

  E.coli

• Tag:

  N-Trx

• Sequence:

  Gly38-Asn114

• Field of Research:

  Immunology

• Endotoxin:

  < 10 EU/mg of the protein as determined by the LAL method.

• Purity:

  > 90% as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  28.3 kDa

• Observed Molecular Weight:

  30 kDa

• Formulation:

  Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

• Species:

  Human