Nav1.8-IN-11

• UNSPSC Description:

  Nav1.8-IN-11 (Example 1) is a Nav1.8 channel inhibitor with a IC50 value of 0.1 nM. Nav1.8-IN-11 can be used in the study of pain disorders[1].

• Target Antigen:

  Sodium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/nav1-8-in-11.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C1=C(C=C(C(F)(F)F)C(Cl)=C1C)OC2=CC=C(C3=C2CCC3)F)NC4=CC=C[N+]([O-])=C4

• Molecular Weight:

  480.84

• References & Citations:

  [1]Xuejun Zhang, et al. Nav1.8 inhibitor and use thereof. WO2023186102A1. 2023-10-05.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2990578-70-4