Purine nucleoside phosphorylase, Microorganism

• UNSPSC Description:

  Purine nucleoside phosphorylase, Microorganism (PNP) is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presence of inorganic orthophosphate as the second substrate, Purine nucleoside phosphorylase catalyzes the breaking of the glycosidic bond between ribose and deoxyribonucleoside to generate purine base and ribose (deoxyribose) -1-phosphate[1].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Enzyme

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/purine-nucleoside-phosphorylase-microorganism.html

• Solubility:

  H2O : ≥ 100 mg/mL

• Smiles:

  [Purine nucleoside phosphorylase, Microorganism]

• References & Citations:

  [1]Bzowska A, et al. Purine nucleoside phosphorylases: properties, functions, and clinical aspects. Pharmacol Ther. 2000 Dec;88(3):349-425.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20°C for 2 years

• Clinical Information:

  No Development Reported

• CAS Number:

  9030-21-1