Connexin 32 (Gap Junction Protein)

• Gene Name:

  [GJB1]

• NCBI Gene ID:

  2705

• Reactivity:

  Human, Mouse, Rat. Others not known.

• Storage Conditions:

  Antibody with azide - store at 2 to 8 °C.
  Antibody without azide - store at -20 to -80 °C.
  Antibody is stable for 24 months. Non-hazardous. No MSDS required.

• Specificity:

  This Ab recognizes a protein of 27-32kDa, identified as Connexin 32. The connexin family of proteins forms hexameric complexes called connexons that facilitate movement of low molecular weight proteins between cells via gap junctions. Connexin proteins share a common topology of four transmembrane alpha-helical domains, two extracellular loops, a cytoplasmic loop and cytoplasmic N- and C-termini. Many of the key functional differences arise from specific amino-acid substitutions in the most highly conserved domains, the transmembrane and extracellular regions. Each of the approximately 20-connexin isoforms produces channels with distinct permeability and electrical and chemical sensitivities; therefore, one connexin usually cannot fully substitute for another.

• Other Gene Names:

  [GJB1; GJB1; CMTX; CX32; CMTX1; CX32; Cx32]

• Short Name:

  [Connexin 32]

• Other Product Names:

  [gap junction beta-1 protein; Gap junction beta-1 protein; gap junction beta-1 protein; gap junction protein beta 1; Connexin-32; Cx32; GAP junction 28 kDa liver protein]

• NCBI GI Number:

  4504005

• NCBI Accession Number:

  NP_000157.1

• NCBI GB Accession Number:

  NM_000166.5

• Uniprot Accession Number:

  P08034