CD86 (Dendritic Cells Maturation Marker) Mouse Monoclonal Antibody

• Gene Name:

  [CD86]

• NCBI Gene ID:

  942

• Reactivity:

  Human, Mouse, Rat

• Storage Conditions:

  Antibody with azide - store at 2°C to 8°C. Non-hazardous. No MSDS required.

• Specificity:

  Recognizes a protein of 70kDa, which is identified as CD86. CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.

• Other Gene Names:

  [CD86; CD86; B70; B7-2; B7.2; LAB72; CD28LG2; CD28LG2]

• Short Name:

  [CD86]

• Other Product Names:

  [T-lymphocyte activation antigen CD86 isoform 4; T-lymphocyte activation antigen CD86; T-lymphocyte activation antigen CD86; CD86 molecule; Activation B7-2 antigen; B70; BU63; CTLA-4 counter-receptor B7.2; FUN-1; CD_antigen: CD86]

• NCBI GI Number:

  332634950

• NCBI Accession Number:

  NP_001193853.1

• NCBI GB Accession Number:

  NM_001206924.1

• Uniprot Accession Number:

  P42081

• CAS Number:

  9007-83-4