RABBIT ANTI CHICKEN INTERFERON GAMMA:Preservative Free

• NCBI Gene ID:

  396054

• Storage Conditions:

  Store at -20 °C only. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
  Shelf Life: 18 months from date of despatch.

• Specificity:

  This item recognizes chicken Interferon gamma (chIFN-gamma). Original studies investigating the properties of chicken Interferon (chIFN), revealed properties similar to mammalian IFN type I (IFNI), and it has since become apparent that there are at least three distinct chicken interferon proteins, designated as chIFN-alpha, chIFN-beta and chIFN-gamma. chIFN-gamma was first identified, when supernatant from chicken spleen cells stimulated with concanavalin A (ConA), displayed macrophage-activating factor (MAF) activity - the principle function of mammalian type II IFN-gamma. Several independent studies have since supported the existence of this chicken homolog, by the cloning of IFN-gamma cDNA from activated chicken T cells and demonstrating that recombinant chicken IFN-gamma strongly upregulates the expression of MHC class II and iNOS genes. This item, can be used to neutralize chIFN-gamma activity and to discriminate the antiviral activity of chIFN-gamma from that of chIFN-alpha and chIFN-beta, see Weining, K.C. et al. for details.

• Other Gene Names:

  [IFNG; IFNG; IFN-gamma]

• Short Name:

  [IFN GAMMA]

• Other Product Names:

  [interferon gamma; Interferon gamma; interferon gamma; IFN-gamma; Interferon-gamma level; interferon-gama; interferon, gamma]

• NCBI GI Number:

  45433518

• NCBI Accession Number:

  NP_990480.1

• NCBI GB Accession Number:

  NM_205149.1

• Uniprot Accession Number:

  P49708

• CAS Number:

  9007-83-4