CD11a/LFA-1A/ITGAL Polyclonal Antibody

• Background:

  ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

• Description:

  This is a CD11a/LFA-1A/ITGAL Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD11A, LFA-1, LFA1A, CD11a, ITGAL

• Gene ID:

  3683

• Swiss Prot:

  P20701

• Reactivity:

  Human, Rat

• Immunogen:

  Recombinant fusion protein of human CD11a/LFA-1A/CD11a/LFA-1A/ITGAL

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  35kDa

• Observed Molecular Weight:

  36kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG