Phospho-IkB alpha (Ser32/S36) Polyclonal Antibody

• Background:

  Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

• Description:

  This is a Phospho-IkB alpha (Ser32/S36) Phospho-Specific Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  I kappa B alpha, I-kappa-B-alpha, IkappaBalpha, IkB-alpha, IKBA, IKBA, IKBalpha, MAD 3, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF kappa B inhibitor alpha, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA, Nuclear factor of kappa light chain gene

• Swiss Prot:

  P25963

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  Synthesized peptide derived from human IκB-α around the phosphorylation site of Ser32/36

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Phospho-Specific Antibody

• Applications:

  WB, IHC-p, IF, ELISA

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000

• Buffer:

  PBS with 0.02% sodium azide, 0.5% protective protein and 50% glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  36 kDa

• Observed Molecular Weight:

  34 kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG