AF647 Anti-Human CD28 Antibody

• Background:

  CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

• Description:

  This is a AF647 Anti-Human CD28 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  PAS2, MNS, HGpMiX, GYPA, GPSAT

• Gene ID:

  940

• Swiss Prot:

  P10747

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Conjugation:

  AF647

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• Host or Source:

  Mouse

• Isotype:

  Mouse IgG1, κ