PerCP Anti-Human CD45 Antibody

• Background:

  CD45 is a 180 - 240 kD single chain type I membrane glycoprotein also known as leukocyte common antigen (LCA) and T200. It is a tyrosine phosphatase expressed on the plasma membrane of all hematopoietic cells, except erythrocytes or platelets. CD45 is a signaling molecule that regulates a variety of cellular processes including cell growth, differentiation, cell cycle, and oncogenic transformation. CD45 plays a critical role in T and B cell antigen receptor-mediated activation by dephosphorylating substrates including p56Lck, p59Fyn, and other Src family kinases. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to bind galectin-1 and to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4.

• Description:

  This is a PerCP Anti-Human CD45 Flow Cytometry Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Receptor-type tyrosine-protein phosphatase C, Ptprc, L-CA, Ly-5, T200, CD45

• Gene ID:

  5788

• Swiss Prot:

  P08575

• Reactivity:

  Human

• Clonality:

  Monoclonal

• Conjugation:

  PerCP

• Type:

  Flow Cytometry Antibody

• Applications:

  FC

• Assay Type:

  Antibody

• Buffer:

  PBS with 0.05% Proclin300, 1% BSA

• Storage Conditions:

  Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

• Host or Source:

  Mouse

• Isotype:

  Mouse IgG1, κ