Anti-LRRC40 Antibody Picoband®, APC Conjugate

• Background:

  Leucine rich repeat containing 40 (LRRC40) is a protein that in humans is encoded by the LRRC40 gene. The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic α/β horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. LRRC40 (leucine rich repeat containing 40) is a 602 amino acid protein that contains 20 LRR (leucine-rich) repeats.

• Description:

  Boster Bio Anti-LRRC40 Antibody Picoband® catalog # A16326-1. Tested in WB, ELISA applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Gene Name:

  LRRC40

• Gene ID:

  55631

• UniProt:

  Q9H9A6

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  E.coli-derived human LRRC40 recombinant protein (Position: R21-D598). Human LRRC40 shares 84.1% amino acid (aa) sequence identity with mouse LRRC40.

• Clonality:

  Polyclonal

• Applications:

  WB,ELISA

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Pijuan, J. , Juan Darío Ortigoza‐Escobar, Ortiz, J. , Adrián Alcalá, María José Calvo, & Cubells, M. , et al. (2021). Plxna2 and lrrc40 as candidate genes in autism spectrum disorder. Autism Research. 2. Liu, H. , Cui, J. , Zhang, Y. , Niu, M. , Xue, X. , & Yin, H. , et al. (2019). Mass spectrometry‐based proteomic analysis of fscn1‐interacting proteins in laryngeal squamous cell carcinoma cells. IUBMB Life, 71(11). 3. Wang, Y. , Du, S. , Zhu, C. , Wang, C. , & Cai, Q. . (2020). Stub1 is targeted by the sumo-interacting motif of ebna1 to maintain epstein-barr virus latency. PLoS Pathogens, 16(3), e1008447.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Observed Molecular Weight:

  72 kDa

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat
  ELISA, 0.1-0.5 μg/ml, -