Anti-Alpha Tubulin/TUBA1C Antibody Picoband®, HRP Conjugate

• Background:

  Tubulin alpha-1C chain is a protein that in humans is encoded by the TUBA1C gene. TUBA1C is an -tubulin isoform involved in mitosis, and its dysregulation has been implicated in tumor progression. There is still no clear understanding of its role in bladder urothelial carcinoma (BLCA).

• Description:

  Boster Bio Anti-Alpha Tubulin/TUBA1C Antibody Picoband® catalog # A03989-2. Tested in WB, IHC, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Gene Name:

  Alpha Tubulin/TUBA1C

• Gene ID:

  84790

• UniProt:

  Q9BQE3

• Host:

  Rabbit

• Reactivity:

  Human,Mouse,Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence at the C-terminus of human TUBA1C.

• Clonality:

  Polyclonal

• Applications:

  WB,IHC,ICC,IF

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Components:

  Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

• References & Citations:

  1. Hu, X., Zhu, H., Chen, B., He, X., Shen, Y., Zhang, X., ... & Xu, X. (2022). The oncogenic role of tubulin alpha-1c chain in human tumours. BMC cancer, 22(1), 498. 2. Wu, Z., Sun, S., Fan, R., & Wang, Z. (2022). Tubulin alpha 1c promotes aerobic glycolysis and cell growth through upregulation of yes association protein expression in breast cancer. Anti-Cancer Drugs, 33(2), 132-141. 3. Gui, S., Chen, P., Liu, Y., Chen, Q., Cheng, T., Lv, S., ... & Cheng, Z. (2021). TUBA1C expression promotes proliferation by regulating the cell cycle and indicates poor prognosis in glioma. Biochemical and biophysical research communications, 577, 130-138.

• Storage Conditions:

  At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

• Applications Notes:

  Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
  Immunohistochemistry, 2-5 μg/ml, Human
  Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human