Anti-MC2 receptor/MC2R Antibody Picoband® (Biotine Conjugate)

• Background:

  Melanocortin-2 receptor (MC2R), also known as ACTH receptor (ACTHR), is a member of the G protein-coupled receptor family. This gene is mapped to 18p11.2. MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency. Alternate transcript variants have been found for this gene.

• Description:

  Boster Bio Anti-MC2 receptor/MC2R Antibody Picoband® catalog # A02306-1. Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Adrenocorticotropic hormone receptor;ACTH receptor;ACTH-R;Adrenocorticotropin receptor;Melanocortin receptor 2;MC2-R;MC2R;ACTHR;

• Gene Name:

  Adrenocorticotropic hormone receptor

• UniProt:

  Q01718

• Host:

  Rabbit

• Reactivity:

  Human,Mouse

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  A synthetic peptide corresponding to a sequence at the C-terminus of human MC2 receptor, different from the related mouse sequence by four amino acids.

• Clonality:

  Polyclonal

• Tissue Specificity:

  Melanocytes and corticoadrenal tissue.

• Applications:

  WB

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

• Function:

  Receptor for corticotropin (ACTH). This receptor is mediated by G proteins (G (s)) which activate adenylate cyclase (cAMP). .

• Storage Conditions:

  Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.1-0.5μg/ml, Mouse, Human
  

• Subcellular Location:

  Cell membrane; Multi-pass membrane protein.

• Protein Name:

  Adrenocorticotropic hormone receptor