Anti-ASC1/TRIP4 Antibody Picoband®

• Background:

  Activating signal cointegrator 1 is a protein that in humans is encoded by the TRIP4 gene. This gene encodes a subunit of the tetrameric nuclear activating signal cointegrator 1 (ASC-1) complex, which associates with transcriptional coactivators, nuclear receptors and basal transcription factors to facilitate nuclear receptors-mediated transcription. This protein is localized in the nucleus and contains an E1A-type zinc finger domain, which mediates interaction with transcriptional coactivators and ligand-bound nuclear receptors, such as thyroid hormone receptor and retinoid X receptor alpha, but not glucocorticoid receptor. Mutations in this gene are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1) .

• Description:

  Boster Bio Anti-ASC1/TRIP4 Antibody Picoband® catalog # A07762-2. Tested in ELISA, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

• Synonyms:

  Protein SOX-15; Protein SOX-12; Protein SOX-20; SOX15; SOX12; SOX20; SOX26; SOX27

• Gene Name:

  SRY-box 15

• UniProt:

  Q15650

• Host:

  Rabbit

• Reactivity:

  Human

• Cross Reactivity:

  No cross-reactivity with other proteins.

• Immunogen:

  E.coli-derived human ASC1/TRIP4 recombinant protein (Position: Q158-D563) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Widely expressed in fetal and adult tissues examined, highest level found in fetal spinal cord and adult brain and testis.

• Applications:

  WB, ELISA

• Field of Research:

  Golgi Proteins, Protein Trafficking, Signal Transduction, Vesicle Transport

• Purification:

  Immunogen affinity purified.

• Concentration:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Form:

  Lyophilized

• Reconstitution:

  Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

• Function:

  Binds to the 5'-AACAAT-3' sequence.

• Storage Conditions:

  At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

• Fragment:

  Rabbit IgG

• Applications Notes:

  Western blot, 0.25-0.5 μg/ml, Human
  ELISA, 0.1-0.5 μg/ml, -
  

• Other Gene Names:

  TRIP4

• Subcellular Location:

  Nucleus.

• Protein Name:

  Chromaffin granule amine transporter