Anti-Phospho-4E-BP1 (T69) EIF4EBP1 Antibody

• Description:

  Boster Bio Anti-Phospho-4E-BP1 (T69) EIF4EBP1 Antibody catalog # A00968T69. Tested in ELISA, IHC, WB applications. This antibody reacts with Mouse, Rat.

• Synonyms:

  Eukaryotic translation initiation factor 4E-binding protein 1;4E-BP1; eIF4E-binding protein 1; Phosphorylated heat- and acid-stable protein regulated by insulin 1; PHAS-I; EIF4EBP1;

• Gene Name:

  EIF4EBP1

• UniProt:

  Q13541

• Host:

  Rabbit

• Reactivity:

  Mouse, Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from mouse 4E-BP1 around the phosphorylation site of Thr69. AA range:35-84

• Clonality:

  Polyclonal

• Applications:

  WB, IHC, ELISA

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  Repressor of translation initiation that regulates EIF4E activity by preventing its assembly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase and mTORC1 pathways.

• Molecular Weight:

  12580 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  Eukaryotic translation initiation factor 4E-binding protein 1

• Protein Name:

  Eukaryotic translation initiation factor 4E-binding protein 1