Anti-R-spondin-2 RSPO2 Antibody

• Description:

  Boster Bio Anti-R-spondin-2 RSPO2 Antibody catalog # A05081. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse.

• Synonyms:

  R-spondin-2; Roof plate-specific spondin-2; hRspo2; RSPO2; UNQ9384/PRO34209;

• Gene Name:

  RSPO2

• UniProt:

  Q6UXX9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Applications:

  WB, ELISA

• Purification:

  RSPO2 antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration:

  1 mg/ml

• Form:

  Liquid

• Function:

  Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Probably also acts as a ligand for frizzled and LRP receptors.

• Molecular Weight:

  28315 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Other Gene Names:

  R-spondin-2

• Subcellular Location:

  Secreted .

• Protein Name:

  R-spondin-2