Anti-Adiponectin Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-Adiponectin Rabbit Monoclonal Antibody catalog # M00509-4. Tested in WB, IHC applications. This antibody reacts with Human.

• Synonyms:

  Glucocorticoid receptor; GR; Nuclear receptor subfamily 3 group C member 1; NR3C1; GRL

• Gene Name:

  Glucocorticoid receptor

• UniProt:

  Q15848

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human Adiponectin

• Clonality:

  Monoclonal

• Clone:

  Clone: 30A69

• Tissue Specificity:

  Widely expressed. In the heart, detected in left and right atria, left and right ventricles, aorta, apex, intraventricular septum, and atrioventricular node as well as whole adult and fetal heart. .

• Applications:

  WB, IHC

• Field of Research:

  Pathways and Processes, Neuroscience, Sensory System, Visual System

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Receptor for glucocorticoids (GC) . Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Could act as a coactivator for STAT5-dependent transcription upon growth hormone (GH) stimulation and could reveal an essential role of hepatic GR in the control of body growth. Involved in chromatin remodeling. May play a negative role in adipogenesis through the regulation of lipolytic and antilipogenic genes expression. .

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC 1:50-1:200

• Other Gene Names:

  ADIPOQ

• Subcellular Location:

  Cytoplasm . Mitochondrion. Nucleus . Cytoplasmic in the absence of ligand, nuclear after ligand- binding.

• Protein Name:

  T-cell surface glycoprotein CD4