Anti-KHSRP Rabbit Monoclonal Antibody

• Description:

  Boster Bio Anti-KHSRP Rabbit Monoclonal Antibody catalog # M02770-2. Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Nucleolysin TIA-1 isoform p40; RNA-binding protein TIA-1; T-cell-restricted intracellular antigen-1; TIA-1; p40-TIA-1; TIA1

• Gene Name:

  Nucleolysin TIA-1 isoform p40

• UniProt:

  Q92945

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthesized peptide derived from human KHSRP

• Clonality:

  Monoclonal

• Clone:

  Clone: 20K75

• Tissue Specificity:

  Widely expressed.

• Applications:

  WB, IHC, ICC, IF, IP

• Field of Research:

  Adaptive Immunity, Apoptosis, Cancer, Cell Biology, Cell Death, DNA/RNA, Epigenetics and Nuclear Signaling, Immunology, Non-CD, Nucleus, RNA Processing, T Cells

• Purification:

  Affinity-chromatography

• Concentration:

  Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.

• Form:

  Liquid

• Reconstitution:

  Restore with deionized water (or equivalent) for reconstitution volume of 1.0 mL

• Function:

  Involved in alternative pre-RNA splicing and regulation of mRNA translation by binding to AU-rich elements (AREs) located in mRNA 3' untranslated regions (3' UTRs) . Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Fragment:

  IgG

• Applications Notes:

  WB 1:500-1:2000
  IHC 1:50-1:200
  ICC/IF 1:50-1:200
  IP 1:50

• Other Gene Names:

  KHSRP

• Subcellular Location:

  Cytoplasmic granule. Nucleus. Accumulates in cytoplasmic stress granules (SG) following cellular damage.

• Protein Name:

  T-cell surface glycoprotein CD3 zeta chain