Recombinant Human FIBP Protein

• Background:

  Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds selectively to acidic fibroblast growth factor (aFGF) . It is postulated that FIBP may be involved in the mitogenic action of aFGF.

• Abbreviation:

  FIBP

• Synonyms:

  Acidic Fibroblast Growth Factor Intracellular-Binding Protein; FGF-1 Intracellular-Binding Protein; FIBP; aFGF Intracellular-Binding Protein

• UniProt:

  O43427

• Accession Number:

  NP_004205.2

• Expression System:

  E.coli

• Tag:

  None

• Sequence:

  Met 1-Asp357

• Field of Research:

  Signal Transduction

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Not Applicable

• Shipping Conditions:

  This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

• Storage Conditions:

  Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

• Calculated Molecular Weight:

  41.8 kDa

• Observed Molecular Weight:

  40-50 kDa

• Formulation:

  Supplied as a 0.2 μm filtered solution of 50mM Tris-HCl, pH8.0.

• Species:

  Human