Recombinant Human CXCL5 Protein

• Background:

  C-X-C Motif Chemokine 5 (CXCL5) is a member of the Intercrine Alpha (Chemokine CXC) family. CXCL5 can be cleaved into the following two chains, ENA-78 (8-78) and ENA-78 (9-78) . In vitro, ENA-78 (8-78) and ENA-78 (9-78) show a threefold higher chemotactic activity for neutrophil granulocytes. CXCL5 is a secreted protein and exercises the functions primarily through interactions with CXCR2. The upregulation of CXCL5 contributes to increased vascularization, tumor grown, and metastasis in many cancers.

• Abbreviation:

  CXCL5

• Synonyms:

  C-X-C Motif Chemokine 5; CXCL5; ENA-78 (1-78) ; ENA-78 (8-78) ; ENA-78 (9-78) ; ENA78; Epithelial-Derived Neutrophil-Activating Protein 78; Neutrophil-Activating Peptide ENA-78; SCYB5; Small-Inducible Cytokine B5

• UniProt:

  P42830

• Accession Number:

  P42830

• Expression System:

  E.coli

• Tag:

  N-His

• Sequence:

  Arg 45-Asn114

• Applications:

  Cell culture

• Field of Research:

  Cardiovascular; immunology

• Endotoxin:

  < 0.1 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 98 % as determined by reducing SDS-PAGE.

• Bioactivity:

  50

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  8.5 kDa

• Observed Molecular Weight:

  12 kDa

• Species:

  Human