Recombinant NEDD4 Monoclonal Antibody

• Background:

  This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.

• Abbreviation:

  NEDD4

• UniProt:

  P46934

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  A synthetic peptide of human NEDD4

• Target:

  NEDD4; NEDD4-1; RPF1

• Clonality:

  Monoclonal

• Clone:

  R06-7C3

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cell Biology; Neuroscience; Epigenetics and Nuclear Signaling

• Purification:

  Affinity Purified

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:2000-1:3000

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  149kDa

• Observed Molecular Weight:

  115kDa

• Isotype:

  IgG