FITC Anti-Human CD28 Antibody[CD28.2]

• Background:

  CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

• Abbreviation:

  CD28

• Gene ID:

  940

• UniProt:

  P10747

• Host:

  Mouse

• Reactivity:

  Human

• Target:

  GPSAT; GYPA; HGpMiX; MNS; PAS2

• Clonality:

  Monoclonal

• Clone:

  CD28.2

• Conjugation:

  FITC

• Applications:

  FCM

• Field of Research:

  Costimulatory Molecules; Immunology

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Mouse IgG1, κ