FITC Anti-Human/Mouse CD44 Antibody[IM7]

• Background:

  CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

• Abbreviation:

  CD44

• Gene ID:

  12505;960

• UniProt:

  P15379; P16070

• Host:

  Rat

• Reactivity:

  Human; Mouse

• Target:

  MDU2MDU3MIC4; CD44; CD44 antigen; CDw44; Epican; LHR; PGP-1; PGP-I; Phagocytic glycoprotein 1; Phagocytic glycoprotein I

• Clonality:

  Monoclonal

• Clone:

  IM7

• Conjugation:

  FITC

• Applications:

  FCM

• Field of Research:

  Cell Adhesion; Cell Biology; Immunology; Stem Cells

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Citation 01:

  https://pubs.acs.org/doi/abs/10.1021/acsnano.4c07213

• Citation 02:

  https://www.sciencedirect.com/science/article/pii/S0142961225000158

• Citation 03:

  https://aacrjournals.org/cancerimmunolres/article-abstract/doi/10.1158/2326-6066.CIR-22-0318/710112

• Citation 04:

  https://www.sciencedirect.com/science/article/pii/S0142961225003102

• Citation 05:

  https://www.sciencedirect.com/science/article/pii/S0168365925001749

• Citation 06:

  https://www.sciencedirect.com/science/article/pii/S1742706124006329

• Citation 07:

  https://pubs.acs.org/doi/abs/10.1021/acs.biomac.1c01076

• Citation 08:

  https://link.springer.com/article/10.1007/s00262-021-02894-8

• Citation 09:

  https://www.nature.com/articles/s41541-025-01132-x

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Rat IgG2b, κ