Elab Fluor® Red 780 Anti-Mouse/Human CD11b Antibody[M1/70]

• Background:

  CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

• Abbreviation:

  CD11b

• Gene ID:

  16409;3684

• UniProt:

  P05555; P11215

• Host:

  Rat

• Reactivity:

  Human; Mouse

• Target:

  CD11 antigen-like family member B; CD11b; CR-3 alpha chain; Integrin alpha-M; Itgam; Leukocyte adhesion receptor MO1

• Clonality:

  Monoclonal

• Clone:

  M1/70

• Conjugation:

  Elab Fluor®Red 780

• Applications:

  FCM

• Field of Research:

  Cell Adhesion; Cell Biology; Costimulatory Molecules; Immunology; Innate Immunity; Neuroscience; Neuroscience Cell Markers

• Concentration:

  5 μL/Test

• Buffer:

  Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

• Citation 01:

  https://advanced.onlinelibrary.wiley.com/doi/abs/10.1002/advs.202415227

• Citation 02:

  https://www.sciencedirect.com/science/article/pii/S0168365925001749

• Citation 03:

  https://breast-cancer-research.biomedcentral.com/articles/10.1186/s13058-024-01904-8

• Recommended Usage:

  The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood) .

• Isotype:

  Rat IgG2b, κ