Anti-LZTS2 Antibody

• Description:

  Boster Bio Anti-LZTS2 Antibody catalog # A07806-2. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Leucine zipper putative tumor suppressor 2

• Gene Name:

  LZTS2

• UniProt:

  Q9BRK4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human LZTS2 (NP_115805.1) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Highly expressed in prostate and testis, and at slightly lower levels in spleen, thymus, uterus, small intestine and colon.

• Applications:

  WB

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Dilution:

  WB: 1:500-1:2000

• Form:

  Liquid

• Function:

  Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.

• Molecular Weight:

  72759 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Leucine zipper putative tumor suppressor 2

• Subcellular Location:

  Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Localized to the centrosome throughout the cell cycle. Localized to the midbody in cells undergoing cytokinesis.

• Protein Name:

  Leucine zipper putative tumor suppressor 2