Anti-PPP1CB Antibody

• Description:

  Boster Bio Anti-PPP1CB Antibody catalog # A04022-2. Tested in WB, IP, IHC applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  Serine/threonine-protein phosphatase PP1-beta catalytic subunit; PP-1B; PPP1CD;3.1.3.16;3.1.3.53; PPP1CB;

• Gene Name:

  PPP1CB

• UniProt:

  P62140

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein corresponding to human PPP1CB aa 100-327.

• Clonality:

  Polyclonal

• Applications:

  WB, IP, IHC

• Purification:

  Protein A purified.

• Form:

  Liquid

• Function:

  Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T- cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208) .

• Molecular Weight:

  37187 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  Serine/threonine-protein phosphatase PP1-beta catalytic subunit

• Subcellular Location:

  Cytoplasm

• Protein Name:

  Serine/threonine-protein phosphatase PP1-beta catalytic subunit