Anti-HCLS1-associated protein X-1 HAX1 Antibody

• Description:

  Boster Bio Anti-HCLS1-associated protein X-1 HAX1 Antibody catalog # A01495-1. Tested in WB, ICC/IF applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  HCLS1-associated protein X-1; HS1-associating protein X-1; HAX-1; HS1-binding protein 1; HSP1BP-1; HAX1; HS1BP1;

• Gene Name:

  HAX1

• UniProt:

  O00165

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human HAX1 (NP_006109.2) .

• Clonality:

  Polyclonal

• Tissue Specificity:

  Ubiquitous. Up-regulated in oral cancers.

• Applications:

  WB, ICC, IF

• Purification:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Form:

  Liquid

• Function:

  Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex (PubMed:26997484) . Slows down the rate of inactivation of KCNC3 channels (PubMed:26997484) . Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools.

• Molecular Weight:

  31621 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  HCLS1-associated protein X-1

• Subcellular Location:

  Mitochondrion

• Protein Name:

  HCLS1-associated protein X-1