Anti-ADP-ribosylation factor 1 ARF1 Antibody

• Description:

  Boster Bio Anti-ADP-ribosylation factor 1 ARF1 Antibody catalog # A01279-1. Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

• Synonyms:

  ADP-ribosylation factor 1; ARF1;

• Gene Name:

  ARF1

• UniProt:

  P84077

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein

• Clonality:

  Polyclonal

• Applications:

  WB, IHC, Flow Cytometry

• Purification:

  ProA affinity purified

• Form:

  Liquid

• Function:

  GTP-binding protein involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex activity; the function is linked to AMPA receptor (AMPAR) trafficking, regulation of synaptic plasicity of excitatory synapses and spine shrinkage during long- term depression (LTD) .

• Molecular Weight:

  20697 MW

• Shipping Conditions:

  Available

• Storage Conditions:

  Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

• Other Gene Names:

  ADP-ribosylation factor 1

• Subcellular Location:

  Golgi apparatus

• Protein Name:

  ADP-ribosylation factor 1