Mouse Tumor Necrosis Factor, Tnf Primacu™ ELISA Kit

• Background:

  Tumor necrosis factor alpha (TNF-alpha), also known as TNF, TNFA or TNFSF2, is the prototypic cytokine of the TNF superfamily, and is a multifunctional molecule involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. Two receptors, TNF-R1 (TNF receptor type 1; CD120a; p55/60) and TNF-R2 (TNF receptor type 2; CD120b; p75/80), bind to TNF-alpha. TNF-alpha protein is produced mainly by macrophages, and large amounts of this cytokine are released in response to lipopolysaccharide, other bacterial products, and Interleukin-1 (IL-1). TNF-alpha is involved in fighting against the tumorigenesis, thus, is regarded as a molecular insight in cancer treatment.TNF-alpha Protein & Antibody Cancer Immunotherapy Immune Checkpoint Immunotherapy Targeted Therapy

• Synonyms:

  Tnfa;Tnfsf2

• Gene ID:

  21926

• Reactivity:

  Mouse

• Target:

  TNF-alpha

• Field of Research:

  Cancer,Cardiovascular,Immunology,Metabolism,Microbiology,Neuroscience,Signal transduction

• Species:

  Mouse